2006 Six Cylinder Engine running rough

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Hello to all the Toyota Users out there.  Hope your ride is running Smooth.

My 2006 TRD 4X4 six(6) cylinder is running pretty rough right now.  Not sure just why. 

My best guess is dirty fuel injectors or bad coils.  I am not sure which.

When it starts it runs rough until I press on the gas and it gets less rough,

"almost" smooth but not quite.

When cold it will "tend" to idle smooth but after it warms up the idle starts

smooth but gets rough and even rougher quickly as the idle time gets longer.

The weather, Dry or Damp, does not seem to change the way the engine runs.

Using a lot more gas as well.

Does anybody have any experience with this kind of a condition?

Would appreciate any and all suggestions.

Thanks to all.

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I am running Fuel treatment. Fuel injector cleaner actually.  My mechanic recognizes the issue, told to use it me to use it and tells me it is running properly other wise.

But I will make sure he checks for vacuum leaks again.

Thanks for responding

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I know this is an old post but for the future: I had a 1999 Tacoma V6 4x4 and it would start to run "rough" like described above, I'd run the injector cleaner through it. I'd let the gas get about 1/4 of a tank, then pour in a whole bottle (Lucas brand) and then let the tank get almost empty. Sometimes I'd do this twice and it would clear it up pretty quick. One time I had a fuel filter full of dirt as I was an avid offroader. 

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